KoCVAM operate the booths in the 35th annual meeting of Korean Society of Toxicology

The KoCVAM operated booths to promote alternative test methods in the 35th annual meeting of Korean Society of Toxicology, and presented the video on eye irritation test method using MCTT HCE™. The KoCVAM also explained the current status of the validation studies in  Korea, international cooperation with ICATM and EURL ECVAM, and KoCVAM’s activities including the publication of test guidelines on alternative test methods and educational workshops on alternative test methods.

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KoCVAM’s Newsletter

The first newsletter of the KoCVAM was published in November. The newsletter compiles a number of articles explaining KoCVAM’s activities and achievements in 2019.

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○ KoCVAM’s activities and achievements
  1. Current status of OECD test guideline adoption and validations studies in KoCVAM
  2. Participation in international validation studies of alternative test methods
  3. Publication of 3 test guidelines on alternative test methods
  4. KoCVAM’s educational workshops

○ KoCVAM’s news
  - Public forum for the 4th industrial revolution in animal bioethics
  - 16th International Annual Meeting of Korean Society for Alternatives to Animal Experiment
  - R&D projects on alternative test methods in 2019
  - Production of videos for the dissemination of alternative test methods adopted by OECD in 2019
  - Recruitment of experts in the area of alternative test methods

Please find more details in the attached newsletter.

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2019 NIFDS Educational Workshop on Alternative Test Methods

09:30~17:00, Friday, Nov 1
Seoul Techno Park, 6th floor, Seoul National University of Science and Technology

□ Participant: 50 participants from research institutes who are interested in alternative test methods and non-clinical laboratories
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□  Main topic :
 ○  Introducing 3 test guidelines on alternative test methods which are adopted by the MFDS in 2019
   ·  Skin sensitisation test method
    - ARE-Nrf2 luciferase Lusens test method
   ·  Skin corrosion test method
    - In vitro skin corrosion: reconstructed human epidermis(RHE) test method
    - In vitro membrane barrier test method for skin corrosion

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 ○  Sharing the information on the technical use and application of alternative test methods
   · Presentation of the video of reconstructed human cornea-like Epitherium test method (MCTT HCE™)

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 ○  Practice in eye irritation alternative test method using human cornea model developed in Korea
   · Application and cleansing process of test chemicals
   · Measurement of cell viability and data calculation, etc.

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2019 Industry-academia-government workshop on alternative test methods

Date: Thursday, Aug 22, 2019
Venue: Baek-eun Kwan, Keimyung University, Daegu, South Korea

□ Participant: 100 participants from industries, regulatory authorities and research institutes who are interested in alternative test methods

□ Main Topic

   ○  Sharing newly updated information about alternative test methods

       (National Institute of Food and Drug Safety, National Institute of Environmental Research, National Institute of Agricultural Sciences)

     · Current status of studies on alternative methods for toxicity evaluation of hazardous chemicals

     · Current status of studies on alternative methods on pesticides
     · KoCVAM’s role as a control tower

   ○ Alternative tests in practice in industry and research institutes

     · The use and application of alternative methods for toxicity prediction 

     · Current status of alternative methods with high-tech convergence technology

     · The use and application of alternative methods in non-clinical study institutes

   ○ Discussion on how to promote the use of alternative tests in Korea 

2019 International Annual Meeting of Korean Society for Alternatives to Animal Experiments(KSAAE)

Date: Friday, Aug 23, 2019
Venue: Baek-eun Kwan, Keimyung University, Daegu, South Korea

□ Objective: To exchange on advanced knowledge & the current development of “in vitro alternative tests in practice”

□ Main topic
   ○ Alternative tests in practice in industry

     · A novel safety assessment using human iPS cell technology
     · Development and application of alternative methods in China
     · Application of reconstructed tissue model
     · Risk assessment using alternative methods
     · In vitro tests for cosmetic efficacy ​

   ○ Alternatives in regulatory science

     · Application of animal alternative methods in Korean Chemicals Regulation

     · Prospects and regulation of alternative methods on pesticides
     · Establishment of new legislation to support new approach methodologies

     · Application of animal alternative methods in Ministry of Food and Drug Safety 

   ○ Alternatives for medical device & cosmetics

     · Practical application of animal alternative test methods for safety evaluation of cosmetics
     · Biological safety assessment and their alternatives for European market approval of medical device
     · Alternatives for opthalmological medical device
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